AC BioScience is focused on personalized molecular therapies; that is, medical care designed to optimize efficiency or therapeutic benefit for particular groups of patients by using molecular profiling.
We identify and develop only those molecules with a previous history of extensive and successful pre-clinical research. The company does not conduct R&D discovery. Its two proprietary cancer molecules have already successfully passed the discovery stage and pre-clinical testing.
The company is also pursuing a drug re-purposing strategy wherever possible. This involves novel uses for existing drugs with well-established safety and tolerance profiles. Our compound for tumor vasculature normalization is a re-purposed drug.
To maximize resources and ensure sustainability, the company operates with a lean organization. This is possible through the deep involvement of the two co-founders in strategic and scientific development and operations, and the obtainment of research grants. Drug development and clinical validation are outsourced to specialist companies or academic institutions.
For one of its molecules, the company is challenging the traditional antiangiogenic approach to cancer therapy. Our neo-adjuvant therapy is designed to improve the efficacy of all types of chemo- and radiotherapy for solid tumors.
Most cancer drugs are usually targeted at a narrow range of specific cancers. However, our strategy covers the entire spectrum of cancers treated with chemo- and radiotherapy. It acts primarily in a neo-adjuvant treatment by enhancing the efficacy of the chemo- and radiotherapy drugs applied.
The company’s initial targets are the treatment of tumoral and immunological pathologies.
One of our projects aims to improve the efficacy of chemo- and radiotherapy in the treatment of solid tumors, using sphingosine-1-phosphate (S.1.p) metabolism modulators as tumor vascular normalizers. A patent is pending for this application.
The company has also acquired a patent for an antitumor cationic amphipathic peptide (CAP6). It belongs to a new generation of cancer drugs with limited side effects and generally greater efficacy.
Our “success by design” business model starts with the identification of new medical strategies for the treatment of cancer.
AC BioScience’s objective is to turn innovation into economic value and to secure optimum protection for its intellectual property. To this end, the company has been diligently protecting its innovations, research and validation work by filing patent applications or acquiring patents for their broadest applications.
A Swiss government-funded collaborative pre-clinical research project with the Molecular Pharmacology Group of the University of Geneva has started in April 2018. It aims at reinforcing the proof-of-concept supporting the use of sphingosine-1-phosphate metabolism modulators as tumor vascular normalizers.
Professor Christian Auclair maintains a network of partnerships with the leading centers in the fight against cancer in Europe, and in particular with the Institut Gustave Roussy in Paris. Research and clinical work is being performed with the Institut Curie in Paris, the University of British Columbia in Vancouver and EPFL in Lausanne.